Irene Gerlach Selected Research

RG7800

1/2019

The oral splicing modifier RG7800 increases full length survival of motor neuron 2 mRNA and survival of motor neuron protein: Results from trials in healthy adults and patients with spinal muscular atrophy.

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Irene Gerlach Research Topics

Disease

3	Spinal Muscular Atrophy (Progressive Muscular Atrophy) 01/2019 - 01/2016
2	Alzheimer Disease (Alzheimer's Disease) 06/2020 - 01/2017
1	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2019
1	Huntington Disease (Huntington's Disease) 01/2019
1	Muscular Atrophy (Muscle Atrophy) 01/2019
1	Dementia (Dementias) 01/2017
1	Parkinson Disease (Parkinson's Disease) 07/2006

Drug/Important Bio-Agent (IBA)

1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 06/2020
1	RG7800IBA 01/2019
1	Huntingtin ProteinIBA 01/2019
1	Proteins (Proteins, Gene)FDA Link 01/2019
1	Messenger RNA (mRNA)IBA 01/2019
1	sembragilineIBA 01/2017
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2017
1	Memantine (Namenda)FDA Link 01/2017
1	Monoamine Oxidase (MAO)IBA 01/2017
1	Biomarkers (Surrogate Marker)IBA 01/2017
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 07/2006
1	5-HT1A Serotonin ReceptorIBA 07/2006

Therapy/Procedure

1	Therapeutics 01/2016